Respiratory Support & Ventilation

Vapotherm Precision Flow Plus

Hi-VNI Technology for the NICU – vapor-transfer humidified, blended gas through small-bore nasal cannula, with published evidence supporting use as a non-invasive alternative to nCPAP in selected indications.

Preterm neonates with RDS and post-extubation respiratory instability need effective non-invasive support without the nasal trauma and seal-maintenance burden of rigid CPAP interfaces.
Precision Flow Plus delivers Hi-VNI Technology – gas humidified to near-physiologic conditions through a vapor transfer cartridge, with an integral oxygen analyzer for in-line FiO₂ verification. Published prospective studies, including SHINE, have reported non-inferiority to nCPAP for primary respiratory support in preterm neonates and for post-extubation support.

  • Non-inferiority data vs nCPAP in published studies – Reported for primary respiratory support in preterm neonates and for post-extubation support.
  • Reduced nasal-interface burden – Small-prong cannula avoids the rigid mask seal that drives nasal injury with conventional nCPAP.
  • Independent control of FiO₂, flow, and temperature – Three parameters titrated separately within the device’s clinical flow range.
  • Membrane-based humidification – Vapor transfer cartridge maintains near-physiologic humidity along the gas path.
  • Integral oxygen analyzer – In-line FiO₂ verification at the device.
  • Single-patient-use vapor transfer cartridge – replaced per IFU; reduces cross-contamination risk.
  • No mask fitting – small-prong cannula eliminates the seal-maintenance burden of nCPAP interfaces.
  • Same platform spans neonatal, pediatric, and adult use – supports NICU through step-down.

Used in preterm neonates with RDS, post-extubation respiratory instability, and other forms of neonatal respiratory failure where non-invasive support is appropriate. Enables mask-free Hi-VNI Technology with vapor-transfer humidification and continuous FiO₂ verification.

Connect with our clinical team.

For clinical evaluations, implementation support and product selection guidance..

SEND INQUIRY